SCHEMBL2907407

SCHEMBL2907407

CC(=O)ON1CCNCCNCCNCC1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA9 Q16790 1/20 0.37
CHKA P35790 1/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
CHRNB3 Q05901 1/20 0.34
CHRNA6 Q15825 1/20 0.34
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32
SIGMAR1 Q99720 3/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083049 0.98 CA2 (0.38) CA2CA12CA1CA9CHKA
SCHEMBL30598789 0.98 CA2 (0.38) CA2CA12CA1CA9CHKA
Hydrochloric Acid SCHEMBL27687817 0.95 CA2 (0.37) CA2CA12CA1CA9CHKA
SCHEMBL21385233 0.95 CHRNB2 (0.39) CA2CA12CA1CA9CHKA
Hydrochloric Acid SCHEMBL28060532 0.95 CA2 (0.37) CA2CA12CA1CA9CHKA
Water SCHEMBL23356455 0.95 CA2 (0.37) CA2CA12CA1CA9CHKA
SCHEMBL30994809 0.95 CHRNB2 (0.39) CA2CA12CA1CA9CHKA
Propionic Acid SCHEMBL28044756 0.86 FFAR3 (0.37) CA2CA12CA1CA9CHKA
Dimethylformamide SCHEMBL27836612 0.85 TSHR (0.32) CA2CA12CA1CA9SIGMAR1
SCHEMBL253645 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118302203-A Methods of treating cancer 融合制药公司 2024-07-05 CN claimed
CN-110035996-B Novel highly relaxant gadolinium chelates for magnetic resonance imaging 拜耳医药股份公司 2022-08-09 CN claimed
CN-110035996-B Novel highly relaxant gadolinium chelates for magnetic resonance imaging 拜耳医药股份公司 2022-08-09 CN disclosed
EP-1602649-B1 Process for the preparation of monofunctionalized 1,4,7,10-tetraazacyclododecane BRACCO SPA (IT) 2010-08-18 EP disclosed