SCHEMBL29074237

SCHEMBL29074237

CCOC(=O)c1cnc(NC(=O)c2cccc(-c3ccccn3)n2)s1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSUN3 Q9H649 1/20 0.60
NPC1 O15118 5/20 0.53
RAB9A P51151 5/20 0.53
PKM P14618 2/20 0.53
LMNA P02545 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
HSP90AA1 P07900 2/20 0.48
ALDH1A1 P00352 4/20 0.46
TSHR P16473 1/20 0.46
MAPT P10636 5/20 0.45
KMT2A Q03164 3/20 0.45
OPRK1 P41145 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
KDM4E B2RXH2 3/20 0.45
HTT P42858 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALOX15 P16050 1/20 0.45
ADORA3 P0DMS8 2/20 0.44
LCK P06239 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12309919 0.89 NPC1 (0.66) NPC1RAB9APKMLMNAL3MBTL1
SCHEMBL29074212 0.83 NPC1 (0.76) NSUN3NPC1RAB9APKML3MBTL1
SCHEMBL29074231 0.83 LCK (0.52) NPC1RAB9ALMNAL3MBTL1HSP90AA1
SCHEMBL2664533 0.81 ALDH1A1 (0.67) NPC1RAB9APKMLMNAALDH1A1
SCHEMBL29074219 0.76 NSUN3 (0.65) NSUN3NPC1RAB9APKMLMNA
SCHEMBL29074204 0.75 NSUN3 (1.00) NSUN3NPC1RAB9APKMLMNA
SCHEMBL22510080 0.75 TP53 (0.55) RAB9ALMNAALDH1A1MAPTKMT2A
SCHEMBL29670209 0.75 ALDH1A1 (0.68) NPC1RAB9ALMNAL3MBTL1ALDH1A1
SCHEMBL3593014 0.75 ALDH1A1 (0.68) NPC1RAB9ALMNAL3MBTL1ALDH1A1
SCHEMBL29074201 0.74 NPC1 (0.60) NSUN3NPC1RAB9ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751195-B Bipyridine compound, pharmaceutically acceptable salt thereof, preparation method and application 杭州科兴生物化工有限公司 2025-03-07 CN disclosed
CN-116751195-A Bipyridine compound, pharmaceutically acceptable salt thereof, preparation method and application 杭州科兴生物化工有限公司 2023-09-15 CN disclosed