SCHEMBL29074271

SCHEMBL29074271

Fc1ccc(C=Cc2ccccc2)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 13/20 0.55
HTR2A P28223 2/20 0.49
HTR2C P28335 2/20 0.49
KCNH2 Q12809 2/20 0.49
TUBB4A P04350 1/20 0.47
TUBB P07437 1/20 0.47
TUBA3C P0DPH7 1/20 0.47
TUBA1B P68363 1/20 0.47
TUBA4A P68366 1/20 0.47
TUBB4B P68371 1/20 0.47
TUBB3 Q13509 1/20 0.47
TUBB2A Q13885 1/20 0.47
TUBB8 Q3ZCM7 1/20 0.47
TUBA3E Q6PEY2 1/20 0.47
TUBA1A Q71U36 1/20 0.47
TUBA1C Q9BQE3 1/20 0.47
TUBB6 Q9BUF5 1/20 0.47
TUBB2B Q9BVA1 1/20 0.47
TUBB1 Q9H4B7 1/20 0.47
TTR P02766 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723352 0.81 NFE2L2 (0.78) NFE2L2HTR2AHTR2CKCNH2
SCHEMBL723353 0.81 NFE2L2 (0.78) NFE2L2HTR2AHTR2CKCNH2
SCHEMBL1755404 0.81 NFE2L2 (0.78) NFE2L2HTR2AHTR2CKCNH2
SCHEMBL722335 0.81 NPC1 (0.51) NFE2L2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9239678 0.81 NFE2L2 (0.59) NFE2L2
SCHEMBL9239673 0.81 NFE2L2 (0.59) NFE2L2
SCHEMBL722334 0.81 NPC1 (0.51) NFE2L2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9233615 0.79 NFE2L2 (0.57) NFE2L2HTR2AHTR2CKCNH2
SCHEMBL9233618 0.79 NFE2L2 (0.57) NFE2L2HTR2AHTR2CKCNH2
SCHEMBL14254170 0.78 NFE2L2 (0.55) NFE2L2HTR2AHTR2CKCNH2TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751137-A Method for preparing chloro aromatic compound by photo-induced nitroarene denitration chlorination 华中师范大学 2023-09-15 CN disclosed