SCHEMBL9239673

SCHEMBL9239673

Fc1cc(Cl)c(/C=C/c2ccccc2)cc1F

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 13/20 0.59
CHAT P28329 1/20 0.44
TRPA1 O75762 1/20 0.44
PLAU P00749 1/20 0.42
PLAT P00750 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9239678 1.00 NFE2L2 (0.59) NFE2L2CHATTRPA1PLAUPLAT
SCHEMBL9233618 0.90 NFE2L2 (0.57) NFE2L2CHATTRPA1
SCHEMBL9233615 0.90 NFE2L2 (0.57) NFE2L2CHATTRPA1
SCHEMBL9235723 0.81 NFE2L2 (0.65) NFE2L2CHATTRPA1
SCHEMBL9235728 0.81 NFE2L2 (0.65) NFE2L2CHATTRPA1
SCHEMBL29074271 0.81 NFE2L2 (0.55) NFE2L2
SCHEMBL722334 0.76 NPC1 (0.51) NFE2L2CHAT
SCHEMBL722335 0.76 NPC1 (0.51) NFE2L2CHAT
SCHEMBL9236793 0.74 NFE2L2 (0.59) NFE2L2
SCHEMBL9236789 0.74 NFE2L2 (0.59) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0635469-A1 2,4,5-Trihalogeno-stilbenes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-25 EP claimed
EP-0635469-A1 2,4,5-Trihalogeno-stilbenes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-25 EP disclosed