Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577504 | 0.81 | TSHR (0.36) | DPP4TSHRF2TAAR1TRPA1 | |
| SCHEMBL9049616 | 0.79 | PTGS1 (0.53) | TSHRMAOBCYP2D6 | |
| SCHEMBL9493266 | 0.77 | TSHR (0.46) | MIFDPP4TSHRF2TRPA1 | |
| SCHEMBL10404000 | 0.77 | MIF (0.42) | MIFDPP4TSHRF2TAAR1 | |
| SCHEMBL10402172 | 0.77 | MAP2K7 (0.37) | MIFDPP4TSHRF2LMNA | |
| SCHEMBL10577509 | 0.76 | DPP4 (0.32) | DPP4TSHRF2TAAR1TRPA1 | |
| SCHEMBL16569811 | 0.71 | LMNA (0.35) | LMNACYP2D6TDP1 | |
| SCHEMBL3956655 | 0.69 | TSHR (0.46) | DPP4TSHRF2TAAR1HTR2A | |
| SCHEMBL28385338 | 0.69 | DPP4 (0.38) | MIFDPP4TSHRF2TAAR1 | |
| SCHEMBL185790 | 0.69 | MIF (0.41) | MIFDPP4TSHRF2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789604-A | 1,3, 4-substituted 2-thioether pyridazine derivative and preparation method thereof | 浙大城市学院 | 2023-09-22 | — | — | CN | disclosed |