Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404000 | 0.77 | MIF (0.42) | CYP2D6LMNAMIFDPP4KMT2A | |
| SCHEMBL29076099 | 0.77 | MIF (0.33) | CYP2D6LMNAMIFDPP4F2 | |
| SCHEMBL9493266 | 0.77 | TSHR (0.46) | ALDH1A1LMNAMIFDPP4MAPK1 | |
| SCHEMBL3716722 | 0.76 | LMNA (0.42) | ALDH1A1SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL4390656 | 0.74 | TSHR (0.38) | ALDH1A1CYP2D6LMNAMAPK1KMT2A | |
| SCHEMBL27673266 | 0.71 | ALDH1A1 (0.36) | ALDH1A1SRCCYP2D6LMNAMAPK1 | |
| SCHEMBL9328653 | 0.70 | TSHR (0.37) | TSHR | |
| SCHEMBL9328658 | 0.70 | TSHR (0.37) | TSHR | |
| SCHEMBL3956655 | 0.69 | TSHR (0.46) | CYP2D6LMNADPP4F2TSHR | |
| SCHEMBL2048984 | 0.69 | CES2 (0.41) | SRCCYP2D6LMNADPP4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | disclosed |
| US-4175185-A | ESTERIFICATION, IMINOHALOGENATION, ETHERIFICATION, HYDROLYSIS, DEESTERIFICATION | MEIJI SEIKA KAISHA LTD. (JP) | 1979-11-20 | — | — | US | disclosed |
| US-4159984-A | METAL AND PROTON DONOR | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-3989685-A | FROM PENICILLIN-1-OXIDE | SHINOGI & CO., LTD. (JA) | 1976-11-02 | — | — | US | disclosed |