Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904547 | 0.92 | PPARD (0.48) | TRPA1KMT2AMEN1PPARDPPARA | |
| SCHEMBL2904008 | 0.92 | KMT2A (0.50) | TRPA1KMT2AMEN1PPARDPPARA | |
| SCHEMBL2901229 | 0.91 | PPARD (0.47) | KMT2AMEN1PPARDPPARAPPARG | |
| SCHEMBL2901188 | 0.91 | RAB9A (0.46) | TRPA1KMT2AMEN1PPARDPPARA | |
| SCHEMBL2906810 | 0.88 | PPARD (0.46) | KMT2AMEN1PPARDPPARAPPARG | |
| SCHEMBL2903759 | 0.88 | PPARD (0.49) | KMT2AMEN1PPARDPPARAMAPT | |
| SCHEMBL2901278 | 0.88 | KMT2A (0.47) | TRPA1KMT2AMEN1PPARDPPARA | |
| SCHEMBL2901332 | 0.86 | PPARD (0.49) | PPARDPPARAPPARGALDH1A1L3MBTL1 | |
| SCHEMBL2906321 | 0.86 | ALDH1A1 (0.43) | KMT2AMEN1PPARDPPARAMAPT | |
| SCHEMBL2903628 | 0.81 | PPARD (0.57) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951692-B1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-08-18 | — | — | EP | claimed |