Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591662 | 0.82 | HDAC1 (0.43) | KMT2ANPC1MAPK1TSHRHSD17B10 | |
| SCHEMBL30377609 | 0.81 | NR1H2 (0.58) | MAPK1NR1H2ESR2 | |
| SCHEMBL2594044 | 0.81 | NOS3 (0.47) | KMT2ANPC1HPGDGAASMN1; SMN2 | |
| SCHEMBL28759740 | 0.78 | KMT2A (0.35) | KMT2ANPC1MAPK1HPGDTSHR | |
| SCHEMBL22466192 | 0.78 | GAA (0.39) | KMT2AHPGDGAASMN1; SMN2HSD17B10 | |
| SCHEMBL27940431 | 0.78 | HPGD (0.47) | MAPK1HPGDGAASMN1; SMN2HTT | |
| SCHEMBL8194675 | 0.75 | NOS3 (0.47) | KMT2AHPGDGAASMN1; SMN2HTT | |
| SCHEMBL29077465 | 0.74 | MAPT (0.40) | KMT2ANPC1MAPK1HPGDGAA | |
| SCHEMBL23705865 | 0.73 | AOC3 (0.44) | NPC1HTR2B | |
| SCHEMBL5316006 | 0.73 | ESR2 (0.39) | KMT2ANPC1HPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783190-A | N- (phenylaminocarbonyl) tetrahydroisoquinolines and related compounds as modulators of GPR65 | 帕蒂奥斯治疗有限公司 | 2023-09-19 | — | — | CN | disclosed |