Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172800 | 0.84 | SMYD3 (0.42) | NPC1ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL13411081 | 0.80 | LMNA (0.51) | EPHX2NPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL28723331 | 0.78 | NPC1 (0.36) | EPHX2NPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL29077624 | 0.77 | ATM (0.39) | ALDH1A1LMNAHDAC1HDAC2MAPT | |
| SCHEMBL24571244 | 0.76 | EPHX2 (0.40) | EPHX2NPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL13411083 | 0.74 | EPHX2 (0.49) | EPHX2NPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL29191942 | 0.73 | EPHX2 (0.41) | EPHX2POLBSMYD3TSHRATM | |
| SCHEMBL13411082 | 0.73 | TSHR (0.45) | EPHX2NPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL28759274 | 0.73 | TP53 (0.51) | ALDH1A1LMNAKDM4EHTTMAPT | |
| SCHEMBL28660967 | 0.71 | TP53 (0.54) | ALDH1A1LMNAMAPTCYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783205-A | Compounds for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 尼坎治疗公司 | 2023-09-19 | — | — | CN | disclosed |