Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 6/20 | 0.44 |
| ▸ | TGM2 | P21980 | 6/20 | 0.44 |
| ▸ | TGM1 | P22735 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TGM6 | O95932 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640991 | 1.00 | F13A1 (0.44) | F13A1TGM2TGM1SMN1; SMN2HTT | |
| SCHEMBL24571938 | 0.93 | TGM2 (0.49) | F13A1TGM2TGM1SMN1; SMN2HTT | |
| SCHEMBL29640929 | 0.93 | TGM2 (0.49) | F13A1TGM2TGM1SMN1; SMN2HTT | |
| SCHEMBL30690902 | 0.85 | F13A1 (0.43) | F13A1TGM2TGM1SMN1; SMN2HTT | |
| SCHEMBL24571634 | 0.84 | BRD4 (0.43) | SMN1; SMN2HTTALDH1A1PKMTSHR | |
| SCHEMBL27298282 | 0.83 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNAPKMCCR5 | |
| SCHEMBL29077488 | 0.82 | F13A1 (0.51) | F13A1TGM2TGM1SMN1; SMN2HTT | |
| SCHEMBL30690890 | 0.82 | F13A1 (0.51) | F13A1TGM2TGM1SMN1; SMN2HTT | |
| SCHEMBL30990611 | 0.81 | PKM (0.52) | F13A1TGM2TGM1SMN1; SMN2HTT | |
| SCHEMBL24571712 | 0.81 | TMEM97 (0.45) | F13A1TGM2TGM1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783205-A | Compounds for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 尼坎治疗公司 | 2023-09-19 | — | — | CN | disclosed |