Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26154073 | 0.76 | CHRNA7 (0.40) | DHODHHRH3SLC6A3MEN1KMT2A | |
| SCHEMBL23630658 | 0.73 | NNMT (0.41) | MEN1KMT2AACACB | |
| SCHEMBL26081151 | 0.72 | DHODH (0.44) | DHODHHRH3ADRB1ADRB3SLC6A3 | |
| SCHEMBL16763014 | 0.72 | CHRNA7 (0.41) | MEN1KMT2AACACB | |
| SCHEMBL28355063 | 0.71 | PIK3CA (0.35) | — | |
| SCHEMBL25344789 | 0.71 | DHODH (0.51) | DHODHMEN1KMT2A | |
| SCHEMBL27710771 | 0.71 | NNMT (0.39) | MEN1KMT2AACACB | |
| SCHEMBL29077941 | 0.70 | KDM4E (0.49) | HRH3KMT2A | |
| SCHEMBL8799763 | 0.68 | ALOX5 (0.58) | — | |
| SCHEMBL22585602 | 0.67 | L3MBTL1 (0.48) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390917-A | MRGX2 antagonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-07-04 | — | — | CN | disclosed |