Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.52 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30518022 | 1.00 | SIGMAR1 (0.52) | SIGMAR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL30518143 | 0.85 | GRIN2B (0.69) | HDAC6GRIN2BHDAC1HDAC4KCNH2 | |
| SCHEMBL29078102 | 0.85 | GRIN2B (0.69) | HDAC6GRIN2BHDAC1HDAC4KCNH2 | |
| SCHEMBL23335840 | 0.78 | PIM1 (0.56) | HRH3F2PIM1PIM2 | |
| SCHEMBL16356212 | 0.77 | DRD4 (0.57) | SIGMAR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15171524 | 0.75 | PRKAA2 (0.57) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL15171781 | 0.74 | DRD4 (0.54) | SIGMAR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16356215 | 0.74 | DRD4 (0.58) | SIGMAR1KCNH2 | |
| SCHEMBL15171776 | 0.71 | DRD4 (0.55) | SIGMAR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15708019 | 0.71 | MAOA (0.50) | SIGMAR1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535343-A | Hydroxamic acid compound and application thereof | 温州医科大学 | 2023-08-04 | — | — | CN | claimed |
| CN-116535343-A | Hydroxamic acid compound and application thereof | 温州医科大学 | 2023-08-04 | — | — | CN | disclosed |