Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078102 | 1.00 | GRIN2B (0.69) | GRIN2BHDAC6HDAC1HDAC4KCNH2 | |
| Befuraline SCHEMBL30036410 | 0.86 | GRIN2B (0.91) | GRIN2BALDH1A1MEN1KMT2APOLB | |
| Befuraline SCHEMBL499156 | 0.86 | GRIN2B (0.91) | GRIN2BALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4991177 | 0.85 | GRIN2B (0.77) | GRIN2BALDH1A1MEN1KMT2APOLB | |
| Befuraline SCHEMBL4320804 | 0.85 | GRIN2B (0.88) | GRIN2BALDH1A1MEN1KMT2APOLB | |
| SCHEMBL29078247 | 0.85 | SIGMAR1 (0.52) | GRIN2BHDAC6HDAC1HDAC4KCNH2 | |
| SCHEMBL30518022 | 0.85 | SIGMAR1 (0.52) | GRIN2BHDAC6HDAC1HDAC4KCNH2 | |
| SCHEMBL6501271 | 0.79 | GRIN2B (0.70) | GRIN2BALDH1A1MEN1KMT2APOLB | |
| SCHEMBL16599028 | 0.78 | ALDH1A1 (0.78) | GRIN2BALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29078165 | 0.77 | HDAC6 (1.00) | HDAC6HDAC1HDAC4KCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535343-A | Hydroxamic acid compound and application thereof | 温州医科大学 | 2023-08-04 | — | — | CN | claimed |
| CN-116535343-A | Hydroxamic acid compound and application thereof | 温州医科大学 | 2023-08-04 | — | — | CN | disclosed |