Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP5 | P51878 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585249 | 1.00 | CHKA (0.47) | CHKASMN1; SMN2GAAL3MBTL1HTT | |
| SCHEMBL30585265 | 0.92 | ALDH1A1 (0.45) | CHKASMN1; SMN2L3MBTL1LMNAFAAH | |
| SCHEMBL29078366 | 0.92 | ALDH1A1 (0.45) | CHKASMN1; SMN2L3MBTL1LMNAFAAH | |
| SCHEMBL29078392 | 0.89 | HTR7 (0.51) | SMN1; SMN2LMNAALDH1A1HTR7HTR6 | |
| SCHEMBL30585255 | 0.89 | HTR7 (0.51) | SMN1; SMN2LMNAALDH1A1HTR7HTR6 | |
| SCHEMBL29078415 | 0.88 | FAAH (0.50) | CHKASMN1; SMN2LMNAFAAHACHE | |
| SCHEMBL30585243 | 0.88 | FAAH (0.50) | CHKASMN1; SMN2LMNAFAAHACHE | |
| SCHEMBL29078375 | 0.84 | CHKA (0.50) | CHKASMN1; SMN2LMNAFAAHACHE | |
| SCHEMBL30585266 | 0.84 | CHKA (0.50) | CHKASMN1; SMN2LMNAFAAHACHE | |
| SCHEMBL30585247 | 0.80 | HTR7 (0.46) | CHKASMN1; SMN2LMNAALDH1A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |