Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078390 | 0.84 | ALDH1A1 (0.72) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL977214 | 0.81 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL4627292 | 0.80 | LMNA (0.67) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL29078371 | 0.78 | ALDH1A1 (0.64) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL6492795 | 0.76 | POLB (0.67) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL30585248 | 0.76 | ALDH1A1 (0.61) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL14427198 | 0.76 | KMT2A (0.68) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL8919985 | 0.76 | MEN1 (0.64) | SMN1; SMN2LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL978086 | 0.75 | MEN1 (0.61) | SMN1; SMN2LMNAALDH1A1MAPTPOLB | |
| SCHEMBL16824855 | 0.75 | POLB (0.73) | SMN1; SMN2LMNAALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |