Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078391 | 0.90 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNASMN1; SMN2CYP2C19 | |
| SCHEMBL29078365 | 0.87 | CYP2C19 (0.61) | ALDH1A1MAPTLMNASMN1; SMN2CYP2C19 | |
| SCHEMBL29078396 | 0.81 | CYP2C19 (0.59) | ALDH1A1MAPTLMNASMN1; SMN2CYP2C19 | |
| SCHEMBL29078403 | 0.78 | SMN1; SMN2 (1.00) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL4627292 | 0.78 | LMNA (0.67) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL29078373 | 0.77 | HTR1A (0.48) | POLBMEN1KMT2ASIRT6 | |
| SCHEMBL29078376 | 0.77 | KMT2A (0.69) | ALDH1A1MAPTLMNASMN1; SMN2CYP2C19 | |
| SCHEMBL30585259 | 0.75 | ALDH1A1 (0.73) | ALDH1A1MAPTLMNACYP2C19MAPK1 | |
| SCHEMBL29078430 | 0.75 | ALDH1A1 (0.73) | ALDH1A1MAPTLMNACYP2C19MAPK1 | |
| SCHEMBL16824855 | 0.74 | POLB (0.73) | ALDH1A1MAPTLMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |