Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911915 | 0.97 | GAA (0.53) | CSF1RMAPTGAAEGFRCA2 | |
| SCHEMBL2907516 | 0.93 | CSF1R (0.60) | CSF1RMAPTGAAEGFRCA2 | |
| SCHEMBL2913641 | 0.92 | CSF1R (0.65) | CSF1REGFR | |
| SCHEMBL2905235 | 0.90 | KCNH2 (0.61) | CSF1RMAPTGAAEGFRCA2 | |
| SCHEMBL2910963 | 0.90 | CSF1R (0.60) | CSF1RMAPTGAA | |
| SCHEMBL2904777 | 0.88 | CSF1R (0.64) | CSF1REGFR | |
| SCHEMBL2910871 | 0.88 | MAPT (0.64) | CSF1RMAPTGAAEGFRCA2 | |
| SCHEMBL2911172 | 0.88 | MAPT (0.52) | CSF1RMAPTGAAEGFRCA2 | |
| SCHEMBL2912246 | 0.87 | KCNH2 (0.62) | CSF1RMAPTGAAEGFRCA2 | |
| SCHEMBL2912768 | 0.86 | CA2 (0.51) | CSF1RMAPTGAAEGFRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |