Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079225 | 1.00 | DPP4 (0.44) | DPP4AAK1MMP13MTNR1AMTNR1B | |
| SCHEMBL30461876 | 0.86 | RIPK1 (0.43) | DPP4AAK1MMP13CTSSCTSK | |
| SCHEMBL25185778 | 0.84 | CTSS (0.48) | AAK1MMP13CTSSCTSKPTPN1 | |
| SCHEMBL6320615 | 0.84 | CTSS (0.48) | AAK1MMP13CTSSCTSKPTPN1 | |
| SCHEMBL25179491 | 0.82 | AAK1 (0.40) | AAK1MMP13CTSSCTSKPTPN1 | |
| SCHEMBL31276458 | 0.79 | AAK1 (0.40) | DPP4AAK1MMP13MTNR1AMTNR1B | |
| SCHEMBL22444868 | 0.79 | AAK1 (0.37) | AAK1MMP13CTSSCTSKPTPN1 | |
| SCHEMBL1401163 | 0.77 | CTSS (0.46) | AAK1MMP13CTSSCTSK | |
| SCHEMBL7248901 | 0.77 | CTSS (0.46) | AAK1MMP13CTSSCTSK | |
| SCHEMBL7435174 | 0.77 | MMP13 (0.44) | AAK1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165071-A | Oxo-spiro indoline compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-116813697-A | Halogenated benzene ring-spiro compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-09-29 | — | — | CN | disclosed |