Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | STAT3 | P40763 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079338 | 0.86 | MEN1 (0.63) | SMN1; SMN2STAT3MEN1KMT2AHTT | |
| SCHEMBL24254549 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2STAT3MEN1KMT2AHTT | |
| SCHEMBL29079332 | 0.82 | BCHE (0.58) | SMN1; SMN2MEN1KMT2AHTTNLRP3 | |
| SCHEMBL8365160 | 0.81 | ALDH1A1 (0.76) | MEN1KMT2ANLRP3ALDH1A1HPGD | |
| SCHEMBL29079342 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2STAT3MEN1KMT2AHTT | |
| SCHEMBL28335090 | 0.79 | MEN1 (1.00) | SMN1; SMN2MEN1KMT2AHTTPOLB | |
| SCHEMBL11679178 | 0.79 | MEN1 (0.77) | SMN1; SMN2STAT3MEN1KMT2AHTT | |
| SCHEMBL2455559 | 0.78 | MEN1 (0.66) | SMN1; SMN2MEN1KMT2ANLRP3ALDH1A1 | |
| SCHEMBL8090356 | 0.78 | MEN1 (0.74) | SMN1; SMN2STAT3MEN1KMT2AHTT | |
| SCHEMBL4007599 | 0.78 | MEN1 (0.74) | SMN1; SMN2STAT3MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417279-A | Phenoxyacetic acid compound, isomer thereof, pharmaceutically acceptable salt or solvate thereof, pharmaceutical composition and medical application | 中国人民解放军军事科学院军事医学研究院 | 2024-01-19 | — | — | CN | disclosed |
| CN-116803977-A | Preparation method and application of phenoxyacetic acid derivative | 中国人民解放军军事科学院军事医学研究院 | 2023-09-26 | — | — | CN | disclosed |