Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19766406 | 0.86 | TLR8 (0.40) | TLR8MAOB | |
| SCHEMBL16167418 | 0.79 | MAOB (0.59) | MAOAMAOBCYP19A1 | |
| SCHEMBL27922486 | 0.76 | MAOA (0.31) | MAOAMAOBCYP19A1 | |
| SCHEMBL12802106 | 0.76 | KMT2A (0.33) | — | |
| SCHEMBL16682341 | 0.76 | GFER (0.59) | MAOAMAOBCYP19A1 | |
| SCHEMBL10492548 | 0.75 | XDH (0.41) | CYP19A1 | |
| SCHEMBL9495607 | 0.73 | XDH (0.40) | — | |
| SCHEMBL865451 | 0.72 | MAOA (0.34) | MAOAMAOBCYP19A1 | |
| SCHEMBL12802272 | 0.71 | TSHR (0.43) | — | |
| SCHEMBL12802091 | 0.71 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490705-B | N-macrocyclic amide compound, preparation method thereof and application thereof as medicine | 成都凡诺西生物医药科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-115490705-A | N-macrocyclic amide compound, preparation method thereof and application thereof as medicine | 成都凡诺西生物医药科技有限公司 | 2022-12-20 | — | — | CN | disclosed |