SCHEMBL865451

SCHEMBL865451

[CH2]CCc1cc(N)cc(N)c1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
CYP19A1 P11511 2/20 0.33
GFER P55789 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
CYP3A4 P08684 1/20 0.30
CASP1 P29466 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27585750 0.79 IDO1 (0.41) MAOBALDH1A1TSHR
SCHEMBL12583989 0.77 MAOB (0.44) MAOAMAOBCYP19A1GFERALDH1A1
SCHEMBL2672471 0.77 CYP3A4 (0.33) MAOAMAOBCYP19A1GFERALDH1A1
SCHEMBL7208354 0.75 MAOB (0.65) MAOAMAOBCYP19A1ALDH1A1CYP3A4
SCHEMBL18469205 0.74 TAAR1 (0.43) GFERALDH1A1RECQL
SCHEMBL7590672 0.72 TDP1 (0.42) MAOAMAOBCYP19A1GFERALDH1A1
SCHEMBL3958673 0.72 GFER (0.68) MAOAMAOBCYP19A1GFERALDH1A1
SCHEMBL6130297 0.72 ALDH1A1 (0.36) MAOAALDH1A1TSHR
SCHEMBL10492672 0.72 CNR1 (0.38) MAOAMAOBCYP19A1GFERALDH1A1
SCHEMBL29080413 0.72 TLR8 (0.32) MAOAMAOBCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115595159-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly 奇美实业股份有限公司(TW) 2023-01-13 CN disclosed
CN-115368914-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 奇美实业股份有限公司 2022-11-22 CN disclosed
CN-115368913-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 奇美实业股份有限公司 2022-11-22 CN disclosed
CN-114507149-A Diamine compound, polymer, alignment agent, alignment film, and liquid crystal display element 奇美实业股份有限公司 2022-05-17 CN disclosed
CN-109085722-B Method for manufacturing liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2022-05-10 CN disclosed
CN-113930248-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2022-01-14 CN disclosed
CN-113930247-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2022-01-14 CN disclosed
CN-113773858-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly 奇美实业股份有限公司 2021-12-10 CN disclosed
CN-109207170-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2021-12-10 CN disclosed
CN-112852446-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2021-05-28 CN disclosed
US-8329823-B2 Photocrosslinkable materials ROLIC AG (CH) 2012-12-11 US disclosed
US-8173749-B2 Photocrosslinkable materials ROLIC AG (CH) 2012-05-08 US disclosed
US-20120076952-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2012-03-29 US disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed
EP-1801097-A1 Photocrosslinkable materials Rolic AG (CH) 2007-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD MAOA 285/4885MAOB 286/4885CYP19A1 1568/4885
US-20120076952-A1 PHOTOCROSSLINKABLE MATERIALS DDC, PARG, ALAD MAOA 285/4885MAOB 286/4885CYP19A1 1568/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 MAOA 717/4885MAOB 1140/4885CYP19A1 2506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.