SCHEMBL29080968

SCHEMBL29080968

Cc1cc(C)cc([PH](=O)F)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 3/20 0.36
HSP90AA1 P07900 1/20 0.36
CCR6 P51684 1/20 0.36
TPMT P51580 1/20 0.35
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
C1S P09871 1/20 0.33
PRSS3 P35030 1/20 0.33
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1305676 0.77 ALDH1A1 (0.40) ALDH1A1TSHRHSP90AA1CCR6TPMT
SCHEMBL29080989 0.75 ACHE (0.48) ALDH1A1TSHRHSP90AA1CYP3A4MAPK1
SCHEMBL28973807 0.74 ALDH1A1 (0.38) ALDH1A1TSHRHSP90AA1CCR6TPMT
SCHEMBL28264040 0.72 ALDH1A1 (0.41) ALDH1A1TSHRHSP90AA1CCR6TPMT
SCHEMBL14246454 0.72 ALDH1A1 (0.36) ALDH1A1TSHRHSP90AA1CCR6TPMT
SCHEMBL28664090 0.72 ACHE (0.44) ALDH1A1TSHRTDP1ACHE
Ammonia Solution, Strong SCHEMBL17670042 0.70 ALDH1A1 (0.39) ALDH1A1TSHRHSP90AA1CCR6TPMT
SCHEMBL28425258 0.67 ALDH1A1 (0.57) ALDH1A1TSHRHSP90AA1CCR6TPMT
SCHEMBL19376983 0.67 ALDH1A1 (0.57) ALDH1A1TSHRHSP90AA1CCR6TPMT
SCHEMBL341533 0.67 ALDH1A1 (0.67) ALDH1A1TSHRHSP90AA1CCR6TPMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 CN disclosed