Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304360 | 0.81 | ACHE (0.52) | ACHEHSP90AA1MGLLALDH1A1MAPK1 | |
| SCHEMBL31327834 | 0.81 | ACHE (0.52) | ACHEHSP90AA1MGLLALDH1A1MAPK1 | |
| SCHEMBL24782677 | 0.79 | ACHE (0.50) | ACHEHSP90AA1MGLLALDH1A1MAPK1 | |
| SCHEMBL14246473 | 0.77 | ACHE (0.48) | ACHEHSP90AA1MGLLALDH1A1MAPK1 | |
| SCHEMBL9441888 | 0.77 | ACHE (0.48) | ACHEALDH1A1MAPK1PARP1TSHR | |
| SCHEMBL2154244 | 0.76 | ACHE (0.46) | ACHEALDH1A1MAPK1PARP1TSHR | |
| SCHEMBL29080968 | 0.75 | ALDH1A1 (0.36) | ACHEHSP90AA1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL28826532 | 0.74 | ACHE (0.44) | ACHEHSP90AA1MGLLALDH1A1MAPK1 | |
| SCHEMBL24783821 | 0.71 | ACHE (0.41) | ACHEALDH1A1MAPK1NPC1NPSR1 | |
| SCHEMBL28664090 | 0.70 | ACHE (0.44) | ACHEMGLLALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113583042-B | Preparation method of phosphoryl fluoride compound | 烟台大学 | 2023-08-29 | — | — | CN | disclosed |