Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyruvate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyruvate SCHEMBL27978365 | 0.85 | TSHR (0.43) | PEPDTSHRTHPOFFAR3LCK | |
| Pyruvate SCHEMBL180812 | 0.85 | TSHR (0.43) | PEPDTSHRTHPOFFAR3LCK | |
| Pyruvate SCHEMBL4306224 | 0.85 | TSHR (0.43) | PEPDTSHRTHPOFFAR3LCK | |
| Pyruvate SCHEMBL20481778 | 0.82 | TSHR (0.40) | PEPDTSHRTHPOFFAR3LCK | |
| Phosphoric Acid SCHEMBL2874997 | 0.78 | — | — | |
| Phosphoric Acid SCHEMBL2867050 | 0.75 | CA2 (0.33) | CA2 | |
| Acetic Acid SCHEMBL28050593 | 0.75 | FFAR3 (0.58) | TSHRTHPOFFAR3LCKFYN | |
| Acetic Acid SCHEMBL2420520 | 0.75 | — | — | |
| Pyruvate SCHEMBL10583422 | 0.75 | — | — | |
| Methacrylic Acid SCHEMBL7649955 | 0.73 | PEPD (0.43) | PEPDTSHRFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114975925-B | Phosphorus-graphene doped composite graphite negative electrode material and preparation method thereof | 广东凯金新能源科技股份有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-114551818-B | Nano silicon composite particles, negative plate and solid lithium battery | 万向一二三股份公司 | 2023-10-03 | — | — | CN | claimed |
| CN-114975925-B | Phosphorus-graphene doped composite graphite negative electrode material and preparation method thereof | 广东凯金新能源科技股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114551818-B | Nano silicon composite particles, negative plate and solid lithium battery | 万向一二三股份公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-114628649-B | Preparation method and application of cobalt-supplementing high-nickel low-cobalt ternary cathode material | 万向一二三股份公司 | 2023-10-03 | — | — | CN | disclosed |