Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25199386 | 0.92 | CTSS (0.51) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL25199383 | 0.92 | CTSS (0.51) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL2532056 | 0.90 | CTSS (0.48) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL143763 | 0.87 | CTSS (0.57) | CTSSCTSLCTSBCTSKSMN1; SMN2 | |
| SCHEMBL4179836 | 0.85 | CTSS (0.62) | CTSSCTSLCTSBCTSKSMN1; SMN2 | |
| SCHEMBL1151498 | 0.85 | CTSS (0.65) | CTSSCTSLCTSBCTSKSMN1; SMN2 | |
| SCHEMBL2206561 | 0.85 | MEN1 (0.47) | CTSSCTSLCTSBMEN1KMT2A | |
| SCHEMBL2796110 | 0.85 | CTSS (0.47) | CTSSCTSLCTSBCTSKCCR1 | |
| SCHEMBL3331774 | 0.84 | CTSL (0.47) | CTSSCTSLCTSBMEN1KMT2A | |
| SCHEMBL8981223 | 0.83 | CTSS (0.67) | CTSSCTSLCTSBCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164829-A1 | A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150089-A1 | A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |