Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25199386 | 1.00 | CTSS (0.51) | CTSSCTSLCTSBCTSKDPP4 | |
| SCHEMBL2908157 | 0.92 | CTSS (0.50) | CTSSCTSLCTSBCTSKDPP4 | |
| SCHEMBL30137703 | 0.87 | CTSS (0.49) | CTSSCTSLCTSBCTSKDPP4 | |
| SCHEMBL2532056 | 0.85 | CTSS (0.48) | CTSSCTSLCTSBCTSKDPP4 | |
| SCHEMBL21777407 | 0.84 | CTSL (0.47) | CTSSCTSLCTSBSMN1; SMN2LMNA | |
| SCHEMBL21777408 | 0.84 | CTSL (0.47) | CTSSCTSLCTSBSMN1; SMN2LMNA | |
| SCHEMBL1151498 | 0.83 | CTSS (0.65) | CTSSCTSLCTSBCTSKSMN1; SMN2 | |
| SCHEMBL21858202 | 0.82 | CTSB (0.46) | CTSSCTSLCTSBCTSKDPP4 | |
| SCHEMBL143763 | 0.82 | CTSS (0.57) | CTSSCTSLCTSBCTSKSMN1; SMN2 | |
| SCHEMBL29002107 | 0.81 | CTSL (0.42) | CTSSCTSLCTSBCTSKDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
| US-20230271917-A1 | AMINO ACIDS | PARABILIS MEDICINES, INC. | 2023-08-31 | — | — | US | disclosed |
| EP-4185599-A2 | STAPLED PEPTIDES AND METHODS THEREOF | Fog Pharmaceuticals, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| EP-4185284-A1 | AMINO ACIDS | Fog Pharmaceuticals, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| CN-116113635-A | Spiro compounds as melanocortin 4 receptor antagonists and uses thereof | 辉瑞公司 | 2023-05-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | CTSS 2634/4885CTSL 1197/4885CTSB 2258/4885 |
| US-20230271917-A1 | AMINO ACIDS | NPPA, QPCTL, PTMS | CTSS 1840/4885CTSL 549/4885CTSB 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.