Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909840 | 0.88 | GSK3B (0.55) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL2909829 | 0.86 | HCRTR1 (0.41) | CNR1CNR2HCRTR1 | |
| SCHEMBL2913408 | 0.85 | GSK3B (0.43) | GSK3BCNR1CNR2DPP4 | |
| SCHEMBL2911861 | 0.83 | GSK3B (0.46) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL2911764 | 0.83 | GSK3B (0.46) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL2912712 | 0.83 | GSK3B (0.46) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL2911030 | 0.83 | GSK3B (0.46) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL2911621 | 0.78 | GSK3B (0.47) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL1219461 | 0.78 | GSK3B (0.49) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL1219591 | 0.76 | CNR1 (0.43) | CNR1CNR2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |