Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of 1-Methylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Methylimidazole SCHEMBL28230726 | 0.97 | NFKB1 (0.94) | — | |
| 1-Methylimidazole SCHEMBL7857428 | 0.97 | — | — | |
| 1-Methylimidazole SCHEMBL556550 | 0.97 | — | — | |
| 1-Methylimidazole SCHEMBL27664516 | 0.97 | NFKB1 (0.94) | — | |
| 1-Methylimidazole SCHEMBL27756040 | 0.97 | — | — | |
| 1-Methylimidazole SCHEMBL9198896 | 0.97 | NFKB1 (0.94) | — | |
| 1-Methylimidazole SCHEMBL29205021 | 0.94 | — | — | |
| 1-Methylimidazole SCHEMBL20112 | 0.94 | — | — | |
| 1-Methylimidazole SCHEMBL9244221 | 0.94 | NFKB1 (1.00) | — | |
| 1-Methylimidazole SCHEMBL4954973 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114471720-B | Organometallic catalysts and their use | 中国石油化工股份有限公司 | 2023-08-29 | — | — | CN | disclosed |