SCHEMBL29083585

SCHEMBL29083585

CCc1cc(CC)c(COCCl)c(CC)c1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.33
PTGS2 P35354 1/20 0.32
HSPA5 P11021 1/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29083615 0.80 PTGS2 (0.32) PTGS2HSPA5MEN1GAAKMT2A
SCHEMBL12895703 0.77 TDP1 (0.41) PTGS2HSPA5MEN1GAAKMT2A
SCHEMBL509442 0.76 HSPA5 (0.35) AKT1PTGS2HSPA5MEN1GAA
SCHEMBL1760666 0.73 DHFR (0.44) PTGS2HSPA5MEN1GAAKMT2A
SCHEMBL9517687 0.72 SRC (0.34) PTGS2HSPA5MEN1GAAKMT2A
SCHEMBL9517681 0.72 PTGS2 (0.32) PTGS2HSPA5MEN1GAAKMT2A
SCHEMBL27214784 0.69 NQO1 (0.42) HSPA5MEN1GAAKMT2A
SCHEMBL18242007 0.69 HSPA5 (0.36) PTGS2HSPA5MEN1GAAKMT2A
SCHEMBL8734181 0.67 HSPA5 (0.35) AKT1PTGS2HSPA5MEN1GAA
SCHEMBL18378504 0.67 HSPA5 (0.35) PTGS2HSPA5MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813666-A Phosphine ligand compound with benzyl alcohol group and preparation method and application thereof 中国石油化工股份有限公司 2023-09-29 CN claimed
CN-116813666-A Phosphine ligand compound with benzyl alcohol group and preparation method and application thereof 中国石油化工股份有限公司 2023-09-29 CN disclosed
CN-116813451-A Substituted benzyl alcohol compound and preparation method and application thereof 中国石油化工股份有限公司 2023-09-29 CN disclosed