Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509442 | 0.90 | HSPA5 (0.35) | HSPA5PTGS2TP53MEN1GAA | |
| SCHEMBL258575 | 0.81 | L3MBTL1 (0.32) | — | |
| SCHEMBL10788697 | 0.78 | HSPA5 (0.47) | HSPA5PTGS2MEN1GAAKMT2A | |
| SCHEMBL9175914 | 0.77 | L3MBTL1 (0.30) | — | |
| SCHEMBL20669667 | 0.77 | PTGS2 (0.34) | PTGS2TP53TRPA1 | |
| SCHEMBL6915173 | 0.73 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL608037 | 0.73 | PTGS2 (0.39) | HSPA5PTGS2TP53GAATRPA1 | |
| SCHEMBL29232907 | 0.72 | SHBG (0.50) | HSPA5PTGS2MEN1GAAKMT2A | |
| SCHEMBL608019 | 0.71 | AKT1 (0.41) | AKT1TRPA1 | |
| SCHEMBL608321 | 0.71 | AKT1 (0.41) | GAAAKT1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |