SCHEMBL29083597

SCHEMBL29083597

Cc1cc(C)c(COCBr)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.34
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.32
HTR1D P28221 1/20 0.32
HTR1B P28222 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7890511 0.85 HRH3 (0.39) HRH3CYP11B1CYP11B2RAPGEF4HTR1D
SCHEMBL29083589 0.79 ADRA2A (0.38) HTR1DHTR1B
SCHEMBL5702537 0.79 HRH3 (0.35) HRH3CYP11B1CYP11B2RAPGEF4HTR1D
SCHEMBL29083610 0.77 HRH3 (0.34) HRH3CYP11B1CYP11B2RAPGEF4HTR1D
SCHEMBL8997706 0.77 HRH3 (0.34) HRH3CYP11B1CYP11B2RAPGEF4HTR1D
SCHEMBL18092254 0.76 PTPN1 (0.35) HRH3CYP11B1CYP11B2RAPGEF4HTR1D
SCHEMBL18092256 0.74 PTPN1 (0.36) HRH3
SCHEMBL11356421 0.74 HRH3 (0.32) HRH3CYP11B1CYP11B2RAPGEF4HTR1D
SCHEMBL3807690 0.73 HPGD (0.44) HRH3CYP11B1CYP11B2RAPGEF4HTR1D
SCHEMBL12595162 0.72 HPGD (0.34) HRH3CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813666-A Phosphine ligand compound with benzyl alcohol group and preparation method and application thereof 中国石油化工股份有限公司 2023-09-29 CN claimed
CN-116813666-A Phosphine ligand compound with benzyl alcohol group and preparation method and application thereof 中国石油化工股份有限公司 2023-09-29 CN disclosed
CN-116813451-A Substituted benzyl alcohol compound and preparation method and application thereof 中国石油化工股份有限公司 2023-09-29 CN disclosed