Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 10/20 | 0.35 |
| ▸ | NOS3 | P29474 | 5/20 | 0.33 |
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | NOS2 | P35228 | 5/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7890511 | 0.82 | HRH3 (0.39) | HRH3 | |
| SCHEMBL5702537 | 0.76 | HRH3 (0.35) | HRH3 | |
| SCHEMBL18092258 | 0.75 | KDM4E (0.49) | PTPN1TACR1 | |
| SCHEMBL29083597 | 0.74 | HRH3 (0.34) | HRH3 | |
| SCHEMBL29083610 | 0.74 | HRH3 (0.34) | HRH3 | |
| SCHEMBL8997706 | 0.74 | HRH3 (0.34) | HRH3 | |
| SCHEMBL14443339 | 0.74 | HRH3 (0.34) | PTPN1TACR1HRH3 | |
| SCHEMBL18092254 | 0.72 | PTPN1 (0.35) | PTPN1HRH3 | |
| SCHEMBL11356421 | 0.71 | HRH3 (0.32) | HRH3 | |
| SCHEMBL14443342 | 0.71 | NOS3 (0.33) | NOS3NOS1NOS2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008178-B | Novel organoleptic compounds | 国际香料和香精公司 | 2020-09-18 | — | — | CN | disclosed |
| EP-3072875-B1 | ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-3072875-B1 | ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9701605-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701605-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701605-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-07-11 | — | — | US | disclosed |
| CN-106008178-A | Organoleptic compounds | 国际香料和香精公司 | 2016-10-12 | — | — | CN | disclosed |
| US-20160280620-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2016-09-29 | — | — | US | disclosed |
| US-20160280620-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2016-09-29 | — | — | US | disclosed |
| EP-3072875-A1 | ORGANOLEPTIC COMPOUNDS | Belko, Robert P. (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-3072875-A1 | ORGANOLEPTIC COMPOUNDS | Belko, Robert P. (US) | 2016-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280620-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | TRPA1, TRPV1, TRPV5 | PTPN1 4863/4885TACR1 918/4885NOS3 2898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.