Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27400561 | 0.87 | GPR35 (0.51) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8489269 | 0.84 | CES2 (0.52) | CES2MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL27875817 | 0.83 | HSP90AB1 (0.59) | MAPTPOLBALDH1A1SMN1; SMN2GPR35 | |
| SCHEMBL12173885 | 0.83 | ALDH1A1 (0.55) | MAPTPOLBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL27858772 | 0.83 | HSP90AB1 (0.59) | MAPTPOLBALDH1A1GPR35MAPK1 | |
| SCHEMBL16637468 | 0.82 | HPGD (0.56) | POLBALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL12709974 | 0.82 | ALDH1A1 (0.48) | MAPTPOLBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL27724891 | 0.82 | TP53 (0.46) | MAPTPOLBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL28092969 | 0.82 | KMT2A (0.64) | MAPTPOLBALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL27554179 | 0.82 | KDM4E (0.42) | MAPTALDH1A1SMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116850246-A | Traditional Chinese medicine composition for treating eczema scroti and preparation method thereof | 天津赛尔康生物医药科技有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-115054665-B | Traditional Chinese medicine composition for treating eczema scrotum | 宁波市中医院 | 2023-08-29 | — | — | CN | disclosed |