SCHEMBL290853

SCHEMBL290853

c1ccc(NC2CCCc3ccccc32)cc1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
LMNA P02545 1/20 0.60
FADS1 O60427 1/20 0.56
HTT P42858 1/20 0.56
ADRA2A P08913 2/20 0.56
ADRA2B P18089 2/20 0.56
ADRA2C P18825 2/20 0.56
ADRA1A P35348 2/20 0.56
HDAC6 Q9UBN7 1/20 0.54
KCNN3 Q9UGI6 1/20 0.54
ALDH1A1 P00352 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
EPHX1 P07099 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29565502 1.00 KMT2A (0.61) KMT2AMEN1LMNAFADS1HTT
SCHEMBL20415615 0.95 MEN1 (0.56) KMT2AMEN1LMNAFADS1HTT
SCHEMBL9541314 0.89 FADS1 (0.69) KMT2AMEN1LMNAFADS1ADRA2A
SCHEMBL31300377 0.89 FADS1 (0.69) KMT2AMEN1LMNAFADS1ADRA2A
SCHEMBL3564108 0.87 LMNA (0.55) KMT2AMEN1LMNAFADS1HTT
SCHEMBL8811675 0.87 LMNA (0.58) KMT2AMEN1LMNAFADS1HTT
SCHEMBL2115700 0.85 HTT (0.63) KMT2AMEN1LMNAHTTADRA2A
SCHEMBL31285743 0.83 ALDH1A1 (0.60) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL3564275 0.81 MEN1 (0.66) KMT2AMEN1LMNAHTTADRA2A
SCHEMBL29789626 0.81 MEN1 (0.66) KMT2AMEN1LMNAHTTADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170209539-A1 Therapeutic Treatment For Metabolic Syndrome, Type 2 Diabetes, Obesity, Or Prediabetes VEROSCIENCE LLC (US) 2017-07-27 US claimed
US-9655865-B2 Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes VEROSCIENCE, LLC (US) 2017-05-23 US claimed
US-20130274246-A1 Therapeutic Treatment for Metabolic Syndrome, Type 2 Diabetes, Obesity, or Prediabetes VEROSCIENCE, LLC 2013-10-17 US claimed
EP-2579876-A2 THERAPEUTIC TREATMENT FOR METABOLIC SYNDROME, TYPE 2 DIABETES, OBESITY, OR PREDIABETES VeroScience LLC (US) 2013-04-17 EP claimed
WO-2011156248-A2 THERAPEUTIC TREATMENT FOR METABOLIC SYNDROME, TYPE 2 DIABETES, OBESITY, OR PREDIABETES VEROSCIENCE, LLC (US) 2011-12-15 WO claimed
EP-2162003-A1 THERAPEUTIC TREATMENT FOR METABOLIC SYNDROME, TYPE 2 DIABETES, OBESITY, OR PREDIABETES VeroScience LLC (US) 2010-03-17 EP claimed
WO-2008150480-A1 THERAPEUTIC TREATMENT FOR METABOLIC SYNDROME, TYPE 2 DIABETES, OBESITY, OR PREDIABETES VEROSCIENCE, LLC (US) 2008-12-11 WO claimed
US-20080293735-A1 Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes VEROSCIENCE, LLC 2008-11-27 US claimed
US-20050054734-A1 Therapeutic treatment for the metabolic syndrome, type2 diabetes, obesity, or prediabetes CINCOTTA ANTHONY H (US) 2005-03-10 US claimed
US-20230106317-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2023-04-06 US disclosed
CN-113348172-B Compound and organic light emitting device including the same 株式会社LG化学 2022-10-11 CN disclosed
CN-113924307-A Polycyclic compound and organic light-emitting element comprising same 株式会社LG化学 2022-01-11 CN disclosed
CN-113348172-A Compound and organic light emitting device including the same 株式会社LG化学 2021-09-03 CN disclosed
WO-2021107711-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2021-06-03 WO disclosed
WO-2000059489-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PSYCHOTIC AND RELATED DISORDERS USING ZIPRASIDONE METABOLITES SEPRACOR INC. (US) 2000-10-12 WO disclosed
EP-0939841-A1 PREPARATION OF FIBERS CONTAINING INTRINSICALLY CONDUCTIVE POLYMERS Zipperling Kessler & Co (GmbH & Co) (DE) 1999-09-08 EP disclosed
WO-1999035308-A2 ANODICALLY FORMED INTRINSICALLY CONDUCTIVE POLYMER-ALUMINUM OXIDE COMPOSITE AS A COATING ON ALUMINUM ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-07-15 WO disclosed
WO-1999025778-A1 SYNTHESIS AND APPLICATIONS OF INTRINSICALLY CONDUCTIVE POLYMER SALTS OF POLYPHOSPHONIC ACIDS IN ANTI-CORROSION COATINGS ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-05-27 WO disclosed
WO-1999015725-A1 PREPARATION OF FIBERS CONTAINING INTRINSICALLY CONDUCTIVE POLYMERS ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-04-01 WO disclosed
WO-1999016084-A1 ELECTRICALLY CONDUCTIVE BLOCK COPOLYMERS CONTAINING AN INTRINSICALLY CONDUCTIVE POLYMER ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230106317-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CCNL2, NR1H3, NR1H2 KMT2A 1761/4885MEN1 1592/4885LMNA 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.