Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | POLG | P54098 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910744 | 0.94 | ABCB11 (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL4973668 | 0.91 | ABCB11 (0.37) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2908647 | 0.85 | ABCB11 (0.39) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2908325 | 0.84 | FAP (0.42) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2939529 | 0.82 | ABCB11 (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2906962 | 0.81 | ABCB11 (0.36) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2912057 | 0.81 | FAP (0.59) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL3290816 | 0.81 | HSP90AA1 (0.36) | — | |
| SCHEMBL13269227 | 0.80 | SLC22A6 (0.59) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2912951 | 0.79 | FAP (0.47) | ABCB11POLA1POLGFAPSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |