Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | POLG | P54098 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908647 | 0.96 | ABCB11 (0.39) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL4973668 | 0.91 | ABCB11 (0.37) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2910744 | 0.86 | ABCB11 (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2906181 | 0.86 | ABCB11 (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL6053569 | 0.84 | CYP1A2 (0.40) | CYP1A2LMNARAB9ACYP3A4PKM | |
| SCHEMBL2908881 | 0.84 | CYP1A2 (0.40) | CYP1A2LMNARAB9ACYP3A4PKM | |
| SCHEMBL2913547 | 0.83 | FAP (0.43) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL4964071 | 0.82 | LMNA (0.33) | CYP1A2LMNARAB9ACYP3A4PKM | |
| SCHEMBL2914722 | 0.82 | ABCB11 (0.39) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2908593 | 0.81 | ABCB11 (0.38) | ABCB11POLA1POLGFAPSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |