Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27225723 | 0.99 | MEN1 (0.51) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL56293 | 0.88 | OPRD1 (0.58) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL29087308 | 0.87 | MEN1 (0.53) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL16042582 | 0.87 | RORC (0.57) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL18742622 | 0.87 | OPRD1 (0.57) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL3901441 | 0.82 | SMN1; SMN2 (0.49) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL29087388 | 0.81 | RORC (0.60) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL27225766 | 0.80 | HDAC1 (0.50) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL29087323 | 0.80 | OPRK1 (0.51) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL29087283 | 0.79 | OPRD1 (0.48) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |