Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002449 | 0.88 | NPSR1 (0.34) | LMNANPSR1MEN1KMT2A | |
| SCHEMBL4037265 | 0.86 | PKM (0.52) | TSHRHSD17B10PKMSMN1; SMN2GAA | |
| SCHEMBL4037047 | 0.84 | PKM (0.50) | TSHRHSD17B10PKMSMN1; SMN2GAA | |
| SCHEMBL20345497 | 0.84 | TSHR (0.48) | TSHRHSD17B10PKMSMN1; SMN2GAA | |
| SCHEMBL6231175 | 0.77 | TSHR (0.44) | TSHRHSD17B10PKMSMN1; SMN2GAA | |
| SCHEMBL4036133 | 0.77 | TSHR (0.44) | TSHRHSD17B10PKMSMN1; SMN2GAA | |
| SCHEMBL4037262 | 0.76 | TSHR (0.43) | TSHRHSD17B10PKMSMN1; SMN2GAA | |
| SCHEMBL5608040 | 0.73 | TSHR (0.41) | TSHRHSD17B10PKMSMN1; SMN2GAA | |
| SCHEMBL5608366 | 0.73 | TSHR (0.41) | TSHRHSD17B10PKMSMN1; SMN2GAA | |
| SCHEMBL4035390 | 0.73 | TSHR (0.45) | TSHRHSD17B10PKMSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |