Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.74 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16677863 | 0.95 | HDAC6 (0.73) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7303163 | 0.92 | HDAC3 (0.86) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL16678174 | 0.91 | HDAC3 (0.73) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL23352870 | 0.88 | TRPV1 (0.67) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7302565 | 0.87 | KCNK9 (0.76) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL557111 | 0.86 | HDAC6 (0.71) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL23309554 | 0.85 | TRPV1 (0.63) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL23352874 | 0.85 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7301362 | 0.85 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7293270 | 0.85 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732198-B2 | Mono- and multi-layer blown films | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20170081486-A1 | Mono- and Multi-Layer Blown Films | BASF SE (DE) | 2017-03-23 | — | — | US | disclosed |
| US-20160136871-A1 | Mono- and Multi-Layer Blown Films | BASF SE (DE) | 2016-05-19 | — | — | US | disclosed |
| US-9278487-B2 | Mono-and multi-layer blown films | BASF SE (DE) | 2016-03-08 | — | — | US | disclosed |
| US-8492468-B2 | Polypropylene resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20130161875-A1 | MONO-AND MULTI-LAYER BLOWN FILMS | BASF SE (DE) | 2013-06-27 | — | — | US | disclosed |
| US-20110301268-A1 | POLYPROPYLENE RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
| EP-2026965-B1 | MONO- AND MULTI-LAYER BLOWN FILMS | BASF SE (DE) | 2010-09-01 | — | — | EP | disclosed |
| US-20090208718-A1 | Mono-and multi-layer blown films | CIBA CORP. | 2009-08-20 | — | — | US | disclosed |