Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.75 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.75 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293270 | 1.00 | HDAC3 (0.75) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL7303163 | 0.93 | HDAC3 (0.86) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL11138236 | 0.89 | HDAC3 (0.60) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL900928 | 0.87 | DEGS1 (0.75) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8420639 | 0.87 | DEGS1 (0.75) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL899585 | 0.87 | DEGS1 (0.75) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23352874 | 0.86 | HDAC3 (0.75) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL4131602 | 0.86 | HDAC3 (0.75) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL3873116 | 0.86 | NR1H4 (0.81) | HDAC3HDAC6HDAC11HDAC8TRPV1 | |
| SCHEMBL1687867 | 0.86 | NPC1 (0.79) | HDAC3HDAC6HDAC11HDAC8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |