Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.71 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303163 | 0.89 | HDAC3 (0.86) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL2908907 | 0.86 | HDAC6 (0.74) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL16678174 | 0.85 | HDAC3 (0.73) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL16677863 | 0.85 | HDAC6 (0.73) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL21588673 | 0.84 | HDAC6 (0.67) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL25721410 | 0.84 | HDAC6 (0.67) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL14137372 | 0.83 | MEN1 (0.59) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL23352874 | 0.83 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7301362 | 0.83 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7293270 | 0.83 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023921-B2 | Method for inhibiting crystal growth rate of amide compound and method for producing molded article of polyolefin-based resin | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2015-05-05 | — | — | US | disclosed |
| EP-2431415-A1 | METHOD FOR CONTROLLING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN | New Japan Chemical Co., Ltd. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-20120035304-A1 | METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035304-A1 | METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN | MNAT1, RFT1, RTF1 | HDAC6 1008/4885HDAC3 1772/4885HDAC8 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.