Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916924 | 0.90 | KDR (0.53) | KDRNPC1CASP3RAB9ASENP8 | |
| SCHEMBL2916686 | 0.84 | NPC1 (0.54) | KDRNPC1CASP3RAB9ASENP8 | |
| SCHEMBL4018015 | 0.81 | KDR (0.76) | KDRNPC1RAB9ATSHRKMT2A | |
| SCHEMBL4016597 | 0.80 | KDR (1.00) | KDRNPC1TSHRKMT2AL3MBTL1 | |
| SCHEMBL1496366 | 0.80 | KDR (0.66) | KDRNPC1TSHRKMT2AMEN1 | |
| SCHEMBL1496298 | 0.79 | KDR (0.70) | KDRNPC1RAB9ATSHRKMT2A | |
| SCHEMBL1786747 | 0.78 | KDR (0.66) | KDRNPC1RAB9ATSHRKMT2A | |
| SCHEMBL4017151 | 0.77 | KDR (0.78) | KDRNPC1RAB9ATSHRKMT2A | |
| SCHEMBL1785017 | 0.77 | KDR (0.74) | KDRNPC1RAB9ATSHRKMT2A | |
| SCHEMBL4022007 | 0.77 | KDR (0.78) | KDRNPC1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854787-B1 | NOVEL CYCLIC COMPOUND HAVING QUINOLYLALKYLTHIO GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2010-09-01 | — | — | EP | claimed |