Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686416 | 0.87 | CES2 (0.61) | CES1CES2ALDH1A1CYP3A4MAPT | |
| SCHEMBL114583 | 0.86 | CES1 (0.58) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL183462 | 0.86 | CES1 (0.58) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL523842 | 0.86 | CES1 (0.58) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL16760711 | 0.83 | CES1 (0.45) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL29290730 | 0.81 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL28604531 | 0.80 | CES1 (0.46) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL4443220 | 0.80 | CES1 (0.46) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL5425618 | 0.80 | TDP1 (0.54) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1647969 | 0.79 | TDP1 (0.52) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016088138-A1 | DIPHENYLOXIRANES, PROCESS FOR PREPARATION THEREOF, AND ITS USE IN AN ENANTIOSELECTIVE SYNTHESIS OF (+)-SERTRALINE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-09 | — | — | WO | claimed |
| CN-106604935-B | Method for producing terminal-modified conjugated diene polymer, rubber composition, and tire | 株式会社普利司通 | 2019-02-22 | — | — | CN | disclosed |
| CN-109153737-A | The manufacturing method of terminal-modified conjugated diolefin polymer, rubber composition, rubber product and terminal-modified conjugated diolefin polymer | 株式会社普利司通 | 2019-01-04 | — | — | CN | disclosed |
| CN-106604935-A | Method for producing terminal-modified conjugated diene polymer, rubber composition, and tire | 株式会社普利司通 | 2017-04-26 | — | — | CN | disclosed |
| WO-2016088138-A1 | DIPHENYLOXIRANES, PROCESS FOR PREPARATION THEREOF, AND ITS USE IN AN ENANTIOSELECTIVE SYNTHESIS OF (+)-SERTRALINE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-09 | — | — | WO | disclosed |
| CN-102164512-A | Beverage composition and method of reducing degradation of monatin | PEPSICO INC | 2011-08-24 | — | — | CN | disclosed |
| EP-1699873-B1 | COSMETIC APPLICATION OF ROD-COIL POLYMERS | OREAL (FR) | 2010-08-11 | — | — | EP | disclosed |
| US-20070098664-A1 | Cosmetic application of rod-coil copolymers | L'OREAL (FR) | 2007-05-03 | — | — | US | disclosed |
| EP-1699873-A1 | COSMETIC APPLICATION OF ROD-COIL POLYMERS | L'OREAL (FR) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005059032-A1 | COSMETIC APPLICATION OF ROD-COIL POLYMERS | L'OREAL (FR) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070098664-A1 | Cosmetic application of rod-coil copolymers | COIL, CRYAB, CRYZ | CES1 3405/4885CES2 2604/4885TSHR 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.