Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969402 | 0.71 | NOTUM (0.43) | NOTUMDRD2DRD3ADRB1HCAR1 | |
| SCHEMBL559633 | 0.69 | CRHBP (0.46) | NOTUMDRD2DRD3ADRB1HCAR1 | |
| SCHEMBL28598903 | 0.69 | NOTUM (0.50) | NOTUMADRB1HCAR1 | |
| SCHEMBL2094941 | 0.69 | NOTUM (0.41) | NOTUMDRD2DRD3ADRB1HCAR1 | |
| SCHEMBL2753769 | 0.69 | NOTUM (0.44) | NOTUMDRD2DRD3ADRB1HCAR1 | |
| SCHEMBL7220247 | 0.68 | HTR3E (0.41) | — | |
| SCHEMBL32680208 | 0.67 | NOTUM (0.50) | NOTUMDRD2DRD3ADRB1HCAR1 | |
| SCHEMBL7222952 | 0.67 | NOTUM (0.48) | NOTUMP2RX7 | |
| SCHEMBL3255936 | 0.67 | NPC1 (0.53) | NOTUMDRD2DRD3ADRB1P2RX7 | |
| SCHEMBL16202007 | 0.67 | NOTUM (0.42) | NOTUMDRD2DRD3ADRB1HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731038-A | Nitrogen-containing heterocyclic compound, and preparation method and application thereof | 苏州亚盛药业有限公司 | 2023-09-12 | — | — | CN | disclosed |