SCHEMBL29090763

SCHEMBL29090763

N#Cc1ccccc1Oc1cccc(Cl)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.52
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
PIN1 Q13526 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.40
SYK P43405 1/20 0.38
PLAU P00749 1/20 0.37
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37
ERBB3 P21860 1/20 0.37
ERBB4 Q15303 1/20 0.37
GCK P35557 1/20 0.36
AR P10275 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
ADRB2 P07550 1/20 0.36
KDM4E B2RXH2 1/20 0.35
LRRK2 Q5S007 1/20 0.35
ACHE P22303 1/20 0.35
CYP11B1 P15538 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27204009 0.83 L3MBTL1 (0.41) MAP4K4L3MBTL1SMN1; SMN2LMNAKDM4E
SCHEMBL10049643 0.78 MAP4K4 (0.50) MAP4K4POLBGAAPIN1SYK
SCHEMBL30449029 0.78 MAP4K4 (0.50) MAP4K4POLBGAAPIN1SYK
SCHEMBL29390597 0.78 MAP4K4 (0.50) MAP4K4POLBGAAPIN1SYK
SCHEMBL10697201 0.78 L3MBTL1 (0.41) MAP4K4L3MBTL1SMN1; SMN2KDM4E
SCHEMBL958698 0.78 ALDH1A1 (0.53) MAP4K4L3MBTL1SMN1; SMN2LMNAKDM4E
SCHEMBL25342784 0.77 MAP4K4 (0.46) MAP4K4POLBGAAPIN1SYK
SCHEMBL23854012 0.76 KDM4E (0.37) MAP4K4L3MBTL1SYKARKDM4E
SCHEMBL9493242 0.75 L3MBTL1 (0.42) MAP4K4GAAPIN1L3MBTL1KDM4E
SCHEMBL7108791 0.75 MAP4K4 (0.52) MAP4K4POLBGAAPIN1GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116848123-A Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting apparatus 株式会社半导体能源研究所 2023-10-03 CN disclosed