Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24532530 | 1.00 | LTA4H (0.40) | LTA4HSIGMAR1LMNAPOLBGAA | |
| SCHEMBL6132926 | 0.86 | PDK1 (0.46) | LTA4HSIGMAR1 | |
| SCHEMBL6133192 | 0.86 | PDK1 (0.46) | LTA4HSIGMAR1 | |
| SCHEMBL24532343 | 0.86 | PDK1 (0.46) | LTA4HSIGMAR1 | |
| SCHEMBL27952242 | 0.82 | LTA4H (0.40) | LTA4HSIGMAR1POLBGAA | |
| SCHEMBL2465869 | 0.82 | SIGMAR1 (0.54) | SIGMAR1LMNAPOLBGAA | |
| SCHEMBL27706864 | 0.82 | LTA4H (0.40) | LTA4HSIGMAR1POLB | |
| SCHEMBL2465872 | 0.82 | SIGMAR1 (0.54) | SIGMAR1LMNAPOLBGAA | |
| SCHEMBL6133030 | 0.81 | LTA4H (0.44) | LTA4HSIGMAR1 | |
| SCHEMBL22792813 | 0.81 | LTA4H (0.44) | LTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263535-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | Astrazeneca AB (SE) | 2023-10-25 | — | — | EP | disclosed |
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022130270-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2022-06-23 | — | — | WO | disclosed |