Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 5/20 | 0.35 |
| ▸ | ATP4A | P20648 | 3/20 | 0.35 |
| ▸ | ATP4B | P51164 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13058007 | 0.84 | TYMS (0.47) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL14365376 | 0.84 | MEN1 (0.44) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL1075198 | 0.80 | MEN1 (0.41) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL5071828 | 0.80 | LTB4R (0.50) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL29091111 | 0.78 | TLR8 (0.48) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL15553342 | 0.77 | TLR8 (0.49) | TLR8 | |
| SCHEMBL3287768 | 0.76 | ALDH1A1 (0.52) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL27681188 | 0.76 | TLR8 (0.50) | ALDH1A1TLR8 | |
| SCHEMBL18340923 | 0.73 | MASP2 (0.48) | MASP2MEN1ALDH1A1NUDT1KMT2A | |
| SCHEMBL21708401 | 0.73 | ALDH1A1 (0.48) | MASP2MEN1ALDH1A1NUDT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050035-A2 | BENZIMIDAZOLES AND ANALOGS THEREOF AS ANTIVIRALS | ISIS PHARMACEUTICALS, INC. (US) | 2004-06-17 | — | — | WO | disclosed |