Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL559198 | 0.81 | KMT2A (0.36) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL29091649 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL29091679 | 0.80 | SLC6A3 (0.34) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL29091587 | 0.77 | CYP19A1 (0.39) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL30615139 | 0.77 | CYP19A1 (0.39) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL29091683 | 0.76 | RET (0.33) | — | |
| SCHEMBL30615094 | 0.76 | RET (0.33) | — | |
| SCHEMBL22208206 | 0.75 | PDE5A (0.30) | — | |
| SCHEMBL11213463 | 0.75 | PDE5A (0.49) | KDM4EMAPTCYP3A4PKMPOLB | |
| SCHEMBL29118912 | 0.74 | MAPT (0.32) | KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |