Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091650 | 0.86 | KMT2A (0.50) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL559198 | 0.83 | KMT2A (0.36) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL30615139 | 0.81 | CYP19A1 (0.39) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL29091600 | 0.81 | KDM4E (0.39) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL30615194 | 0.81 | NQO2 (0.38) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL29091679 | 0.81 | SLC6A3 (0.34) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL29091666 | 0.81 | NQO2 (0.38) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL29091587 | 0.81 | CYP19A1 (0.39) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL31621002 | 0.80 | SMN1; SMN2 (0.42) | HPGDCYP2C19MAPTTDP1KCNA3 | |
| SCHEMBL11213463 | 0.79 | PDE5A (0.49) | KDM4ECYP3A4MAPTPDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |