Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091649 | 0.86 | ALDH1A1 (0.49) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL29091596 | 0.81 | ALDH1A1 (0.34) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL29091636 | 0.78 | FGFR2 (0.37) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL30615194 | 0.75 | NQO2 (0.38) | KMT2AALDH1A1MEN1KDM4ETUBB1 | |
| SCHEMBL29091587 | 0.75 | CYP19A1 (0.39) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL30615139 | 0.75 | CYP19A1 (0.39) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL29091666 | 0.75 | NQO2 (0.38) | KMT2AALDH1A1MEN1KDM4ETUBB1 | |
| SCHEMBL31621002 | 0.74 | SMN1; SMN2 (0.42) | MAPTHPGDCYP2C19KCNA3GAA | |
| SCHEMBL29091582 | 0.73 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL559198 | 0.73 | KMT2A (0.36) | KMT2AALDH1A1MEN1KDM4ETUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |